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Celebrex is a drug with a pronounced anti-inflammatory, analgesic, and antipyretic effect. It is characterized by high efficiency and affordable price. Unlike many other nonsteroidal anti-inflammatory drugs, it rarely gives side effects. It is released only if there is a doctor’s prescription.

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Celebrex has analgesic, antipyretic and anti-inflammatory effects. It is available in the form of capsules with a gelatin shell. Each capsule contains 200 mg of the active substance called celecoxib.

Celebrex refers to drugs of the non-steroidal anti-inflammatory group. At the same time, it is safer than a number of other drugs belonging to the same category. For example, it rarely leads to the formation of ulcers and does not disrupt the digestive processes. It is well absorbed when taken on an empty stomach and is almost completely (99%) excreted through the liver.

Indications for the use of Celebrex

Supportive treatment for many diseases involves the use of various drugs. The indications for the use of Celebrex include symptomatic therapy. The drug eliminates acute pain attacks, arthritis (osteoarthritis, rheumatoid), spondylitis, algodismenorrhea. It can be used in the complex therapy of adenomatous polyposis to reduce the size and number of adenomatous colorectal polyps.

The use of this drug increases the risk of developing thrombosis in vital organs. Therefore, treatment is recommended to be carried out with minimal effective doses and for a short period of time. This drug does not replace acetylsalicylic acid, since it does not have antiplatelet properties. In the course of therapy, it is necessary to control blood pressure, since there is a risk of developing hypertensio

The use of Celebrex during pregnancy

Symptomatic treatment of various diseases and acute pain attacks in expectant mothers is carried out only with safe drugs that do not affect the development of the fetus. The use of Celebrex during pregnancy is possible according to strict indications. This takes into account the possible risk of side effects in the child and the negative impact on the mother’s body.

The drug is contraindicated for use in the third trimester. The active substance suppresses the production of prostaglandins, which causes disturbances in the contractile activity of the uterus. It is not used during lactation, since the active components are excreted in breast milk.

Contraindications

Any pharmacological agent has a number of restrictions on its use. Consider the contraindications to the use of Celebrex:

  • Hypersensitivity to the active substance and other components of the drug.
  • Intolerance to sulfonamides.
  • Increased risk of allergic reactions when using NSAIDs or acetylsalicylic acid.
  • Use as an analgesic in the postoperative period during coronary artery bypass grafting.

 

If the above recommendations are not followed, there is a risk of developing negative symptoms from all organs and systems.

The drug is taken orally, regardless of the meal, without chewing, washed down with water. Contraindications to use do not differ from those when using other selective NSAIDs. They can always be found in the instructions for the drug.

A study was conducted where Celebrex and Diclofenac were compared. Diclofenac was prescribed with omeprazole to protect the gastrointestinal tract. As a result of the study, it was revealed that patients with rheumatoid arthritis and polyosteoarthrosis who received Celebrex developed clinically significant gastrointestinal complications 4 times less, in contrast to patients receiving Diclofenac. In addition, and when compared with other NSAIDs, Celebrex was recognized as the safest drug of this group in relation to the gastrointestinal tract.

Also, Celebrex has shown itself as a drug that has the least effect on blood pressure, chronic cardiovascular insufficiency, and the development of edema, which is very important for patients suffering from hypertension and other diseases of the cardiovascular system.

The risk of adverse effects on the liver when using Celebrex is also minimal compared to other NSAIDs.